Research - Publications


Hartiala, J., Li, D., Conti, D., Vikman, S., Patel, Y., Tang, W., Brennan, M.
Newman, J., Stephensen, C., Armstrong, P., Hazen, S., Allayee, H., et al. 2011. Genetic contribution of the leukotriene pathway to coronary artery. Human Genetics. 129:6. p617-627

Nutritional Genomics: Dietary Regulation of Gene Function and Human Disease. 2011. Bidlack, W. and R. L. Rodriguez, Taylor and Francis/CRC Press, in press.

Dawson, K., Zhao, L., Adkins, Y., Vemuri, M., Rodriguez, R.L., Gregg, J.P., Kelley, D. S. and Hwang, D.H.  2011. DHA supplementation suppresses LDL receptor and oxidized LDL receptor gene expression in blood cells from hypertriglyceridemic men.  J. Nutritional Biochem. In Press.

Galvez, A.F., Huang, L., Magbanua, M.M.J. Dawson, K., Nandi, S. and R. L. Rodriguez. 2011. Diet-influenced Chromatin Modification and Expression of Chemopreventive Genes by the Soy Peptide, Lunasin, in Nutritional Genomics: Dietary Regulation ofGene Function on Human Disease.  Bidlack, W. and R. L. Rodriguez, eds. Taylor and Francis/CRC Press, in press.

Jun, H-J, Kim, S., Dawson, K., Choi, D-W, Kim, J-S, Rodriguez, R. L. and Lee, S-J. 2011. Effects of Acute Oral Administration of Vitamin C on the Mouse Liver Transcriptome.  J. Med. Food. 14:1-14.

Galvez, A.F., Huang, L., Magbanua, M.M.J. Dawson, K. R. L. Rodriguez. 2011. Differential Expression of Thrombospondin (THBS1) in Turmorigenic and Nontumorigenic Prostate Epithelial Cells in Response to a Chromatin-Binding Soy Peptide.  Nutrition and Cancer 63(4):623-636.

Jun, H-J, Chung, M-J, Dawson, K. Rodriguez, R.L., Houng, S-J, Cho, S-Y, Jeun, J., Kim, J-Y, Kim, K-H, Park, K. W., Kim, C.-T. and Lee, S-J. 2010. Nutrigenomic Analysis of Hypolipidemic Effects of Agastache rugosa Essential Oils in HepG2 Cells and C57BL/6 Mice. Food Sci. Biotechnol. 19(1):219-227.

Choi, Y-M, Jun, H-J, Dawson, K., Rodriguez, R.L., Roh, M-R, Jun, J., Choi, C-H,  Choi, Shim, J-H, Lee, C-H, Lee, S-J, Park, K-H and Lee, S-J.  2010. Effects of the isoflavone puerarin
and its glycosides on melanogenesis in B16 melanocytes. Eur. Food Res. Technol. DOI 10.1007/s00217-010-1251-5.


Dawson, K; Zhao, L; Adkins, Y; Vemuri, M; Rodriguez, R.L.; Kelley, D.S; Hwang, D (2009) Docosahexaenoic acid supplementation suppresses LDL receptor and Oxidized LDL receptor gene expression in blood cells from hypertriglyceridemic men (in prep).

Galvez, A.F; Huang, L; Magbanua, M.M.J; Dawson, K; del Rosario, J; & Rodriguez, R.L; (2009). Epigenetic Regulation of UGT1A1 Expression by the Chromatin-Binding Soy Peptide, Lunasin. (in prep)

Kima, S; Juna, H-J; Dawson, K; Choic, D-W; Kimd, J-S; Rodriguez, R.L; & Leea, S-J. (2009). Effect of high-dose vitamin C on mouse liver 1 transcriptome: A nutritional genomics study. (in prep)

Zoukhri, D; Rawe, I; Singh, M; Kublin, C; Dawson, K; Haddon, W.F; White, E; Hanley, K; Tusé, D; Malyj, W; Papas, A. (2009). Discovery of Putative Salivary Biomarkers for Sjögren's Syndrome Using High Resolution Mass Spectrometry and Bioinformatics. (in prep)

Galvez, A.F; Huang, L; Magbanua, M.M.J; Dawson, K; Rodriguez, R.L; (2009). Upregulation of Chemopreventive Genes by a Chromatin-binding Soy Peptide is Associated with Histone H4-Lysine16 Acetylation in non-tumorigenic but not in tumorigenic prostate epithelial cells. (submitted)

Hawkes, W.C., Wang, T.T.Y., Alkan, Z., Richter, B.D., & Dawson, K. (2009). Selenoprotein W Modulates Control of Cell Cycle Entry. Biological Trace Element Research, 131:229-244.

Padgett, K.A; Lan, R.Y; Leung, P.S; Lleo, A; Dawson, K; Pfeiff, J; Coppel, R.L; Ansari, A.A; & Gershwin, M.E. (2009). Primary billhiary cirrhosis is associated with altered hepatic microRNA expression. J. Autoimmun, 32(3-4):246-53.


Ahmad SM, Haskell MJ, Raqib R, Stephensen CB: Men with low vitamin A stores respond adequately to primary yellow fever and secondary tetanus toxoid vaccination. J Nutr 2008, 138:2276-2283.

Ahmad SM, Haskell MJ, Raqib R, Stephensen CB: Markers of innate immune function are associated with vitamin a stores in men. J Nutr 2009, 139:377-385.

Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, et al.: Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. J Cell Mol Med 2008.

Aronov PA, Hall LM, Dettmer K, Stephensen CB, Hammock BD: Metabolic profiling of major vitamin D metabolites using Diels-Alder derivatization and ultra-performance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 2008, 391:1917-1930.

Atamna H, Nguyen A, Schultz C, Boyle K, Newberry J, Kato H, Ames BN: Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways. FASEB J 2008, 22:703-712.

Bergmark C, Dewan A, Orsoni A, Merki E, Miller ER, Shin MJ, Binder CJ, Horkko S, Krauss RM, Chapman MJ, et al.: A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma. J Lipid Res 2008, 49:2230-2239.

Caulfield MP, Li S, Lee G, Blanche PJ, Salameh WA, Benner WH, Reitz RE, Krauss RM: Direct determination of lipoprotein particle sizes and concentrations by ion mobility analysis. Clin Chem 2008, 54:1307-1316.

Chen W, Wang S, Ma Y, Zhou Y, Liu H, Strnad P, Kraemer FB, Krauss RM, Liu J: Analysis of polymorphisms in the 3' untranslated region of the LDL receptor gene and their effect on plasma cholesterol levels and drug response. Int J Mol Med 2008, 21:345-353.

Chung CS, Stookey J, Dare D, Welch R, Nguyen TQ, Roehl R, Peerson JM, King JC, Brown KH: Current dietary zinc intake has a greater effect on fractional zinc absorption than does longer term zinc consumption in healthy adult men. Am J Clin Nutr 2008, 87:1224-1229.

Cvijanovich NZ, King JC, Flori HR, Gildengorin G, Wong HR: Zinc homeostasis in pediatric critical illness. Pediatr Crit Care Med 2009, 10:29-34.

Fejerman L, John EM, Huntsman S, Beckman K, Choudhry S, Perez-Stable E, Burchard EG, Ziv E: Genetic ancestry and risk of breast cancer among U.S. Latinas. Cancer Res 2008, 68:9723-9728.

Hudes ML, McCann JC, Ames BN: Unusual clustering of coefficients of variation in published articles from a medical biochemistry department in India. FASEB J 2008.

Itsara A, Cooper GM, Baker C, Girirajan S, Li J, Absher D, Krauss RM, Myers RM, Ridker PM, Chasman DI, et al.: Population Analysis of Large Copy Number Variants and Hotspots of Human Genetic Disease. Am J Hum Genet 2009.

Jiang Q, Moreland M, Ames BN, Yin X: A combination of aspirin and gamma-tocopherol is superior to that of aspirin and alpha-tocopherol in anti-inflammatory action and attenuation of aspirin-induced adverse effects. J Nutr Biochem 2008.

Killilea DW, Ames BN: Magnesium deficiency accelerates cellular senescence in cultured human fibroblasts. Proc Natl Acad Sci U S A 2008, 105:5768-5773.

Kim EY, Ham SK, Shigenaga MK, Han O: Bioactive dietary polyphenolic compounds reduce nonheme iron transport across human intestinal cell monolayers. J Nutr 2008, 138:1647-1651.

King JC, Blumberg J, Ingwersen L, Jenab M, Tucker KL: Tree nuts and peanuts as components of a healthy diet. J Nutr 2008, 138:1736S-1740S.

King JC, Rechkemmer G, Geiger CJ: Second International Nuts and Health Symposium, 2007: introduction. J Nutr 2008, 138:1734S-1735S.

King SM, Donangelo CM, Knutson MD, Walter PB, Ames BN, Viteri FE, King JC: Daily supplementation with iron increases lipid peroxidation in young women with low iron stores. Exp Biol Med (Maywood) 2008, 233:701-707.

Krauss RM: Interview. Pharmacogenomics 2008, 9:997-1000.

Krauss RM: What can the genome tell us about LDL cholesterol? Lancet 2008, 371:450-452.

Krauss RM, Mangravite LM, Smith JD, Medina MW, Wang D, Guo X, Rieder MJ, Simon JA, Hulley SB, Waters D, et al.: Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment. Circulation 2008, 117:1537-1544.

Lai CQ, Tucker KL, Choudhry S, Parnell LD, Mattei J, Garcia-Bailo B, Beckman K, Burchard EG, Ordovas JM: Population admixture associated with disease prevalence in the Boston Puerto Rican health study. Hum Genet 2008.

Lal A, Atamna W, Killilea DW, Suh JH, Ames BN: Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts. Redox Rep 2008, 13:2-10.

Layman DK, Clifton P, Gannon MC, Krauss RM, Nuttall FQ: Protein in optimal health: heart disease and type 2 diabetes. Am J Clin Nutr 2008, 87:1571S-1575S.

Long J, Gao F, Tong L, Cotman CW, Ames BN, Liu J: Mitochondrial Decay in the Brains of Old Rats: Ameliorating Effect of Alpha-Lipoic Acid and Acetyl-L: -carnitine. Neurochem Res 2008.

Maki KC, Curry LL, Carakostas MC, Tarka SM, Reeves MS, Farmer MV, McKenney JM, Toth PD, Schwartz SL, Lubin BC, et al.: The hemodynamic effects of rebaudioside A in healthy adults with normal and low-normal blood pressure. Food Chem Toxicol 2008, 46 Suppl 7:S40-46.

Maki KC, Curry LL, Reeves MS, Toth PD, McKenney JM, Farmer MV, Schwartz SL, Lubin BC, Boileau AC, Dicklin MR, et al.: Chronic consumption of rebaudioside A, a steviol glycoside, in men and women with type 2 diabetes mellitus. Food Chem Toxicol 2008, 46 Suppl 7:S47-53.

Maki KC, McKenney JM, Reeves MS, Lubin BC, Dicklin MR: Effects of adding prescription omega-3 acid ethyl esters to simvastatin (20 mg/day) on lipids and lipoprotein particles in men and women with mixed dyslipidemia. Am J Cardiol 2008, 102:429-433.

Mangravite LM, Wilke RA, Zhang J, Krauss RM: Pharmacogenomics of statin response. Curr Opin Mol Ther 2008, 10:555-561.

Mashiyama ST, Hansen CM, Roitman E, Sarmiento S, Leklem JE, Shultz TD, Ames BN: An assay for uracil in human DNA at baseline: effect of marginal vitamin B6 deficiency. Anal Biochem 2008, 372:21-31.

Maynard CL, Hatton RD, Helms WS, Oliver JR, Stephensen CB, Weaver CT: Contrasting roles for all-trans retinoic acid in TGF-{beta}-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells. J Exp Med 2009.

McCann JC, Ames BN: Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction? FASEB J 2008, 22:982-1001.

McCann JC, Hudes ML, Ames BN: Part 2--Unusual clustering of coefficients of variation in published articles from a medical biochemistry department in India. FASEB J 2008.

Medina MW, Gao F, Ruan W, Rotter JI, Krauss RM: Alternative splicing of 3-hydroxy-3-methylglutaryl coenzyme A reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin. Circulation 2008, 118:355-362.

Michlitsch J, Azimi M, Hoppe C, Walters MC, Lubin B, Lorey F, Vichinsky E: Newborn screening for hemoglobinopathies in California. Pediatr Blood Cancer 2008, 52:486-490.

Morris CR, Suh JH, Hagar W, Larkin S, Bland DA, Steinberg MH, Vichinsky EP, Shigenaga M, Ames B, Kuypers FA, et al.: Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease. Blood 2008, 111:402-410.

Nelson EC, Rodriguez RL, Dawson K, Galvez AF, Evans CP: The interaction of genetic polymorphisms with lifestyle factors: implications for the dietary prevention of prostate cancer. Nutr Cancer 2008, 60:301-312.

Ntukidem NI, Nguyen AT, Stearns V, Rehman M, Schott A, Skaar T, Jin Y, Blanche P, Li L, Lemler S, et al.: Estrogen receptor genotypes, menopausal status, and the lipid effects of tamoxifen. Clin Pharmacol Ther 2008, 83:702-710.

Paschou P, Drineas P, Lewis J, Nievergelt CM, Nickerson DA, Smith JD, Ridker PM, Chasman DI, Krauss RM, Ziv E: Tracing sub-structure in the European American population with PCA-informative markers. PLoS Genet 2008, 4:e1000114.

Reiner AP, Barber MJ, Guan Y, Ridker PM, Lange LA, Chasman DI, Walston JD, Cooper GM, Jenny NS, Rieder MJ, et al.: Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. Am J Hum Genet 2008, 82:1193-1201.

Ruby MA, Nomura DK, Hudak CS, Mangravite LM, Chiu S, Casida JE, Krauss RM: Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins. Proc Natl Acad Sci U S A 2008, 105:14561-14566.

Sampath V, Havel PJ, King JC: Calcium supplementation does not alter lipid oxidation or lipolysis in overweight/obese women. Obesity (Silver Spring) 2008, 16:2400-2404.

Schuster GU, Kenyon NJ, Stephensen CB: Vitamin A deficiency decreases and high dietary vitamin A increases disease severity in the mouse model of asthma. J Immunol 2008, 180:1834-1842.

Seibold MA, Wang B, Eng C, Kumar G, Beckman KB, Sen S, Choudhry S, Meade K, Lenoir M, Watson HG, et al.: An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity. Hum Mol Genet 2008, 17:2681-2690.

Shin MJ, Kanaya AM, Krauss RM: Polymorphisms in the peroxisome proliferator activated receptor alpha gene are associated with levels of apolipoprotein CIII and triglyceride in African-Americans but not Caucasians. Atherosclerosis 2008, 198:313-319.

Sulkes D, Brown BG, Krauss RM, Segrest JP, Sniderman AD, Roberts WC: The editor's roundtable: expanded versus standard lipid panels in assessing and managing cardiovascular risk. Am J Cardiol 2008, 101:828-842.

Swarbrick MM, Stanhope KL, Elliott SS, Graham JL, Krauss RM, Christiansen MP, Griffen SC, Keim NL, Havel PJ: Consumption of fructose-sweetened beverages for 10 weeks increases postprandial triacylglycerol and apolipoprotein-B concentrations in overweight and obese women. Br J Nutr 2008, 100:947-952.

Wagner JG, Jiang Q, Harkema JR, Ames BN, Illek B, Roubey RA, Peden DB: Gamma-tocopherol prevents airway eosinophilia and mucous cell hyperplasia in experimentally induced allergic rhinitis and asthma. Clin Exp Allergy 2008, 38:501-511.

Wilke RA, Berg RL, Linneman JG, Zhao C, McCarty CA, Krauss RM: Characterization of low-density lipoprotein cholesterol-lowering efficacy for atorvastatin in a population-based DNA biorepository. Basic Clin Pharmacol Toxicol 2008, 103:354-359.

Yaeger R, Avila-Bront A, Abdul K, Nolan PC, Grann VR, Birchette MG, Choudhry S, Burchard EG, Beckman KB, Gorroochurn P, et al.: Comparing genetic ancestry and self-described race in african americans born in the United States and in Africa. Cancer Epidemiol Biomarkers Prev 2008, 17:1329-1338.


Battle NC, Choudhry S, Tsai HJ, Eng C, Kumar G, Beckman K, Naqvi M, Meade K, Watson HG, Lenoir M, Burchard EG. Ethnic Specific Gene-Gene Interaction between IL-13 and IL-4Ra Among African American Asthmatics. Am J Respir Crit Care Med. 2007 May 1;175(9):881-7.

Beckman KB, Abel KJ, Braun A, Halperin E. Using DNA pools for genotyping trios. Nucleic Acids Res. 2006;34(19):e129.

Cropley JE, Suter CM, Beckman KB, Martin DI. Germ-line epigenetic modification of the murine Avy allele by nutritional supplementation. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17308-12.

Fogg-Johnson, N & Kaput, J. (2007). The State of Nutrigenomics: Update for Food Technologists. Food Technology (in prep).

Golden TR, Beckman KB, Lee AH, Dudek N, Hubbard A, Samper E, Melov S. Dramatic age-related changes in nuclear and genome copy number in the nematode Caenorhabditis elegans. Aging Cell. 2007 Apr;6(2):179-88.

Hawkes, W.C., Wang, T.T.Y., Alkan, Z., Richter, B.D., & Dawson, K. (2007). Gene Expression Profiling in Human Mammary Epithelial Cells Reveals New Potential Targets for Breast Cancer Prevention with Dietary Selenium. Journal of Nutrition. (submitted)

Kaput, J. & Dawson, K. (2007). Complexity of Type 2 Diabetes Mellitus Data Sets Emerging from Nutrigenomic Research: A Case for Dimensionality Reduction. Mutation Research, 622:19-32.

Kaput, J., Noble, J., Hatipoglu, B., Kohrs, K., Dawson, K., & Bartholomew, A. (2007). Application of Nutrigenomic Concepts to Type 2 Diabetes Mellitus. Nutrition, Metabolism, & Cardiovascular Diseases, 17(2):89-103.

Kaput, J. (2007). Editorial Focus: Nutrient Selection through Nutrigenomic Approaches. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology. 292, R204-6.

Kaput, J. Perlina, A., Hatipolgu, B, Bartholomew, A, & Nikolsky, Y (2007). Nutrigenomics: Applications to Pharmacogenomics and Clinical Medicine. Pharmacogenomics. 8, 369-90.

Kaput, J. (2007). International efforts on nutrigenomic health for individuals in the global community. In Personalized Nutrition: Principles and Applications. Kok, F, Bouwman, L, and Desiere, F (Eds). CRC Press. (in press).

Kaput, J., Heil, S, Astley, S, van Leeuwen-Bol. I, & van Ommen, B. (2007). Challenging Homeostasis to Define Biomarkers for Individual Nutrigenomic Health. (in prep.).

Kaput, J. (2007). Developing the Promise of Nutrigenomics through Complete Science and International Collaborations, in Nutrigenomics - Opportunities in Asia. In Forum Nutr. 60. Tai, ES & Gillies, PJ. (Eds), Basel:Karger. pp. 210-24.

Kaput, J. (2007). Developing the promise of nutrigenomics through complete science and international collaborations.Forum Nutr. 60:209-23.

Kima, S-K; Juna, H-J; Choib, D-W; Rodriguez, R.L; Dawson, K; Kim, J.S; & Lee, S-J (2007). Nutrigenomic analysis of hepatic transcriptome of mice consuming high level of vitamin C: Genome-wide analysis of vitamin C intake in murine livers. (in prep).

Kleemann, R, van Erk, M, vd Weij, J, van Ommen, B, Kooistra, T, Kaput, J, Perlina, A, Kaznacheev, V, Melnikov, A, Nikolskaya, T, & Nikolsky, Y. (2007). High Dietary Cholesterol Induces Metabolic Stress Response in Liver as Revealed by Genome-wide Pathway Analysis. Differential Effects of Lipid-modulating Drugs. (in prep.).

Magbanua, M.J., Dawson, K., Huang, L., Galvez, A., & Rodriguez, R. (2007). Soy peptide up-regulates tumor suppressor and other chemopreventive genes in human cancer. (submitted)

Mangravite, L.M., Dawson, K., Davis, R.R., Gregg, J.P., & Krauss, R.M. (2007). Fatty acid desaturase regulation in adipose tissue by dietary composition is independent of weight loss and correlated with plasma triacylglycerol response. American Journal of Clinical Nutrition. 86(3):759-67

Melov, S, Tarnopolsky, MA, Beckman KB, Felkey, K, Hubbard, A. Resistance exercise reverses aging in human skeletal muscle. PloS ONE 2007; 2(5), e465.

Nelson, E.C; Rodriguez, R.L; Dawson, K; Galvez, A.F; Evans, C.P. (2007). he interaction of genetic polymorphisms with lifestyle factors: implications for the dietary prevention of prostate cancer. (in prep).

Ordovas, JM, Corrella, D &. Kaput, J. (2007) Nutrient-gene interactions in lipoprotein metabolism - an overview. Forum Nutr. 60:102-9.

Ordovas, JM, Kaput, J, & Corrella, D. (2007). Nutrition in the Genomics Era: Cardiovascular Disease Risk and the Mediterranean Diet. Molecular Nutrition, 51(10):1293-9.

Tsai, Y.H., Choudhry, S., Kho, J., Beckman, K., Tsai, H.J., Navarro, D., Matallana, H., Castro, R.A., Lilly, C.M., Nazario, S., Rodriguez-Santana, J.R., Casal, J., Torres, A., Salas, J., Chapela, R., Watson, G., Leade, K., Avila, P.C., Rodriguez-Cintron, W., LeNoir, M., Burchard, E.G. The PTGDR Gene is not associated with asthma in three ethnically diverse populations. J Allergy Clin Immunol. 2006 Dec;118(6):1242-8.

Wallace, S., Wakimoto, P, Yang, H and R Rodriguez. Development of an on-line survey to assess training needs in nutritional genomics. The FASEB Journal. 2007;21:lb240.


*Ames, BN, JH Suh and J Lui. Enzymes lose binding affinity (increased Km) for coenzymes and substrates with age: A strategy for remediation. 2006. in Nutrigenomics: Discovering the Path to Personalized Nutrition, John Wiley & Sons, New Jersey, pp. 277-94.

*Ames BN. Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage.
Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17589-94. Epub 2006 Nov 13. PMID: 17101959

Aranda N, Viteri FE, Fernandez-Ballart J, Murphy M, Arija V. Frequency of the hemochromatosis gene (hfe) 282c->y, 63h->d and 65s->c mutations in a general mediterranean population from Tarragona, Spain. Clinical Genetics. In Press, 2006 PMID: 17013646

Atamna, H and Boyle, K. Amyloid-b peptide binds with heme to form a peroxidase: Relationship to the cytopathologies of Alzheimer's disease. 2006. PNAS 103: 3381-6. PMID: 16492752

Beckman, K.B., Abel, K.J., Braun, A., Halperin, E. (2006). Using DNA
pools for genotyping trios. Nucleic Acids Research 34, e129. PMID: 17020923

Cropley, J.E., Suter, C.M., Beckman, K.B., Martin, D.I.K. (2006).
Germline epigenetic modification of the Avy allele by nutritional
supplementation. Proceedings of the National Academy of Sciences 103, 17308-17312. PMID: 17101998

Beckman, K.B., Golden, T.R., Lee, A.H.J., Dudek, N., Hubbard, A.,
Samper, E., Melov, S. (2006). Dramatic age-related changes in nuclear integrity and nuclear genome copy number in the nematode C. elegans.  Aging Cell XX, yyy-zzz (Accepted online: 22-Dec-2006, doi: 10.1111/j. 1474-9726.2006.00273.x).

Casanueva E, Viteri FE, Mares-Galindo M, Meza-Camacho C, Loria A, Schnaas L, Valdes-Ramos R. Weekly iron as a safe alternative to daily supplementation for nonanemic pregnant women. Arch Med Res. 2006;37:674-682. PMID: 16740440

*Dawson, K, Rodriguez, RL, Hawkes, WC and Malyj, W. Biocomputation and the analysis of complex data sets in nutritional genomics, 2006. In Nutrigenomics: Discovering the Path to Personalized Nutrition, John Wiley & Sons, New Jersey, pp. 375-401.

Aoki, C.A., Dawson, K, Kenny, T.P., Gershwin, M.E., & Bowlus, C.L. (2006). Gene expression by PBMC in primary sclerosing cholangitis: Evidence for dysregulation of immune mediated genes. Clinical & Developmental Immunology, 13(2):265-71.  PMID: 17162367

Dawson, K., Rodriguez, R.L., Hawkes, W.C., & Malyj, W. (2006). Making mole hills out of mountains: Reducing the dimensionality of complex datasets in nutritional genomics. In: Kaput, J.A., & Rodriguez, R.L. (Eds.): Nutritional Genomics. New York: Wiley.

Magbanua, M.M.M., Dawson, K., Huang, L., Malyj, W., Gregg, J., Galvez, A., & Rodriguez, R.L. (2006). Nutrient-Gene interaction in involving soy peptide and chemopreventive genes in prostate epithelial cells. In: Kaput, J.A., & Rodriguez, R.L. (Eds.): Nutritional Genomics. New York: Wiley.
Hawkes, W.C., Wang, T., and K. Dawson. (2006). Selenium and gene expression in cultured human mammary cells. FASEB Journal. 20(5), A1069 Part 2.

*Holland, N, Furlong, C, Bastaki, M, Richter, R, Bradman, A, Huen, K, Beckman, K, and Eskenazi, B. Paraoxonase Polymorphisms, Haplotypes and Enzyme Activity in Latino Mothers and Newborns. 2006. Environ. Health Perspect. 14(7):985-91 PMID: 16835048

*Huang L, Kirschke CP, Zhang Y. Decreased intracellular zinc in human tumorigenic prostate epithelial cells: a possible role in prostate cancer progression. 2006. Cancer Cell Int. 6:10. PMID: 16579854

*Kaput, J. 2006.  Diet-Disease Interactions at the Molecular Level:  An experimental paradigm. In Phytochemicals:  Nutrient-Gene Interactions. M. Meskin, Bidlack, WR, and Randoph, RK. (Ed.)  CRC Press.  Pg 23-39. PMID: 7914920

*Kaput, J.An Introduction and Overview of Nutritional Genomics: Application to Type 2 Diabetes and International Nutrigenomics, in Nutrigenomics:  Discovering the Path to Personalized Nutrition.  Editors: Kaput, J and Rodriguez, RL.  Wiley and Sons.  April 2006

*Kaput, J,Astley, S, Ordovas, JM, and van Ommen, B.  2006.  Harnessing Nutrigenomics:  Development of Web-based Communication, Databases, Resources, and Tools.  Genes & Nutrition 1 (1) 5 - 12.

*Krauss, RM and Siri, PW.  Dietary and genetic effects on atherogenic dyslipidemia. 2006. in Nutrigenomics: Discovering the Path to Personalized Nutrition, John Wiley & Sons, New Jersey, pp. 295-304.

*Magbanua, MJM, Dawson, K, Huang, L, Malyj, W, Gregg, J, Galvez, A and Rodriguez, RL.  Nutrient-gene interactions involving soy peptide and chemopreventive genes in prostate epithelial cells. 2006. in Nutrigenomics: Discovering the Path to Personalized Nutrition, John Wiley & Sons, New Jersey, pp. 255-76.

*McCann J, Hudes M, Ames BN. An Overview of Evidence for a Causal Relationship Between Dietary Availability of Choline During Development and Cognitive Function in Offspring. 2006. Neuroscience and Biobehavioral Reviews 30: 696-712. PMID: 16504295

O'Brien, KO, Donangelo, CM, Vargas Zapata, CL, Abrams, SA, Spencer, EM, and King, JC.  Bone calcium turnover during pregnancy and lactation in women with low calcium diets is associated with calcium intake and circulating insulin-like growth factor 1 concentrations. 2006. Am J Clin Nutr 83:317-23. PMID: 16469990

Pena-Rosas J, Viteri F. Effects of routine oral iron supplementation with or without folic acid for women during pregnancy. Cochrane Database Syst Rev. 2006 Jul 19;3:CD004736. PMID: 16856058

*Stephensen CB, Marquis GS, Jacob RA, Kruzich LA, Douglas SD, Wilson CM. Vitamins C and E in adolescents and young adults with HIV infection. 2006. Am J Clin Nutr 83:870-9. PMID: 16600941

*Stephensen CB, Marquis GS, Kruzich LA, Douglas SD, Aldrovandi GM, Wilson CM. Vitamin D status in adolescents and young adults with HIV infection. 2006. Am J Clin Nutr. 83:1135-41. PMID: 16685057

*Tervalon, M and Fernandez, E. Cultural Humility: A contribution to health professional education in nutrigenomics. 2006. in Nutrigenomics: Discovering the Path to Personalized Nutrition, John Wiley & Sons, New Jersey, pp. 403-418.

*Tsai YH, Choudhry S, Kho, J, Beckman K,Tsai HJ, Navarro D, Matallana H, Castro RS, Lilly CM, Nazario S, Rodriguez-Santana JR, Casal J, Torres A, Salas J, Chapela R, Watson HG, Meade K, Avila PC, Rodriguez-Cintron W, LeNoir M, Burchard EG. The PTGDR Gene is not Associated with Asthma in Three Ethnically Diverse Populations. 2006. J Allergy Clin Immun. 118:1242-48. PMID: 17157653


* = Publications that cite the Center grant number P60MD0222



Ames, BN. 2005. Increasing Longevity by Tuning-up Metabolism, EMBO Rep. 6, S20-4. PMID: 15995656

Ames, BN., Atamna, H, and Killilea, D. 2005.  Review: Mineral and Vitamin Deficiencies Can Accelerate the Mitochondrial Decay of Aging. Mol. Aspects Med. 26, 363-78. PMID: 16102804

Berger J, Than HK , Cavalli-Sforza T, Suttilak S, Khan NC , Hoa PT, Quang ND, Viteri  FE. 2005.  Community mobilization and social marketing to promote weekly iron-folate supplementation in women of reproductive age in vietnam: impact on anemia and iron status. Nutr. Rev. in press.

Cavalli-Sforza LT, Berger J, Smitasiri S, Viteri FE.  2005.  Weekly Iron-Folic Acid Supplementation of Women of Reproductive Age: Impact Overview, Lessons Learned, Expansion Plans And Contributions Toward Achievement Of The Millennium Development Goals. Nutr. Rev. in press

Dawson, K, Rodriguez, RL, Malyj, W.  Sample phenotype clusters in Affymetrix gene expression data sets are revealed using Isomap, a nonlinear algorithm. 2005. BMC Bioinformatics 6, 195 (free access)

Jim Kaput*, Jose M. Ordovas*, Lynn Ferguson*, Ben van Ommen*, Raymond L. Rodriguez*, Lindsay Allen*, Bruce N. Ames*, Kevin Dawson*, Bruce German*, Ronald Krauss*, Wasyl Malyj*, Michael C. Archer, Stephen Barnes, Amelia Bartholomew, Ruth Birk, Peter van Bladeren, Kent J. Bradford, Kenneth H. Brown, Rosane Caetano, David Castle, Ruth Chadwick, Stephen Clarke, Karine Clement, Craig A. Cooney, Dolores Corella, Ivana Beatrice Manica da Cruz, Hannelore Daniel, Troy Duster, Sven O.E. Ebbesson, Ruan Elliott, Susan Fairweather-Tait, Jim Felton, Michael Fenech, John W. Finley, Nancy Fogg-Johnson, Rosalynn Gill-Garrison, Michael J Gibney, Peter J. Gillies, Jan-Ake Gustafsson, John L. Hartman IV, Lin He, Jae-Kwan Hwang, Jean-Philippe Jais, Yangsoo Jang, Hans Joost, Claudine Junien, Mitchell Kanter, Warren A. Kibbe, Berthold Koletzko, Bruce R. Korf, Kenneth Kornman, David W. Krempin, Dominique Langin, Denis R. Lauren, Jong Ho Lee, Gilbert A. Leveille, Su-Ju Lin, John Mathers, Michael Mayne, Warren McNabb, John A. Milner, Peter Morgan, Michael Muller, Yuri Nikolsky, Frans van der Ouderaa, Taesun Park, Norma Pensel, Francisco Perez-Jimenez, Kaisa Poutanen, Matthew Roberts, Wim H.M. Saris, Gertrud Schuster, Andrew N. Shelling, Artemis P Simopoulos, Sue Southon, E Shyong Tai, Bradford Towne, Paul Trayhurn, Ricardo Uauy, Willard J. Visek, Craig Warden, Rick Weiss, John Wiencke, Jack Winkler, George L. Wolff, Xi Zhao-Wilson, Jean-Daniel Zucker (*primary authors).  2005.  The Case for Strategic International Alliances to Harness Nutritional Genomics for Public and Personal Health.  British Journal of Nutrition 94, 623-632. (* indicates primary authors). (free access courtesy of the Nutrition Society)

Kaput, J. Decoding the pyramid: a systems - biological approach to nutrigenomics.  2005.  Ann. NY Acad. Sci. 1055, 64 - 679.  PMID: 16387719

Liu, J. and Ames, BN. 2005.  Mitochondrial nutrients: Reducing mitochondrial decay to delay or treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease, In: Neurodegenerative Disorders, Aging and Antioxidants. Editors Y. Luo and L. Packer.

Stephensen, CB, Marquis, GS, Kruzich, LA, Douglas, SD, Wilson, CM.  Immune Activation and Oxidative Damage in HIV-Positive and HIV-Negative Adolescents.  J Acquir Immun Defic Synd 38, 180-90. PMID: 15671803

Stephensen, CB, Marquis, GS, Douglas, SD, Wilson, CM.  2005. Plasma Cytokines and Oxidative Damage in HIV-Positive and HIV-Negative Adolescents and Young Adults: A protective role for IL-10?  Free Radical Research 39, 859-64 PMID: 16036366

Viteri FE. Berger J.  2005.  Importance Of Pre-Pregnancy And Pregnancy Iron Status:  Can Long Term Weekly Preventive Iron And Folic Acid Supplementation Achieve Desirable And Safe Status? Nutr. Rev. in press.


Ames , BN.  A Role for Supplements in Optimizing Health: The Metabolic Tune-Up. 2004. Arch Biochem Biophys. 423, 227-234. PMID: 14989256

Andree KB, Kim J, Kirschke CP, Gregg JP, Paik H, Joung H, Woodhouse L, King JC, and Huang L. Investigation of lymphocyte gene expression for use as biomarkers for zinc status in humans. 2004. J Nutr 134, 1716-1723. PMID: 15226459 (free access)

Atamna, H. Heme, iron, and the mitochondrial decay of ageing. 2004. Ageing Res Rev. 3, 303-318. (Review).  PMID: 15231238.

Atamna, H and Frey, WH. A Role for Heme in Alzheimer's Disease: Heme Binds Amyloid- b and has Altered Metabolism.  2004. PNAS 101, 11153-11158. (free access)

Ames , BN. Delaying the Mitochondrial Decay of Aging. 2004. Ann N Y Acad Sci. 1019, 406-11. PMID: 15247055.

Ferguson, L. R. and Kaput, J.  2004.  Nutritional Genomics and the New Zealand Food Industry. In Food New Zealand.  In Press. Invited Review.

Kaput, J. Diet - disease gene interactions.  2004. Nutrition 20, 26 - 31. PMID: 14698010

Kaput, J and Rodriguez, RL. Nutritional genomics: the next frontier in the postgenomic era. 2004. Physiological Genomics 16, 166 - 177.  (free acess)

Kaput. J, Klein, KG, Reyes, EJ, Kibbe, WA, Cooney, CA, Jovanovic, B, Visek, WJ, Wolff, GL. Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.  2004.  Physiological Genomics 18, 316 - 324. (free access)

Pena-Rosas JP, Viteri FE, Mahomed K. 2004.  Oral iron supplementation with or without folic acid for women during pregnancy. (Protocol) Cochrane Database Syst. Rev., Issue 2. Art. No.: CD004736. DOI: 10.1002/14651858.CD004736.

Zhang, X, Leung, SM, Morris, CR, and Shigenaga, MK.  2004. Evaluation of a Novel, Integrated Approach Using Functionalized Magnetic Beads, Bench-Top MALDI-TOF-MS with Prestructured Sample Supports, and Pattern Recognition Software for Profiling Potential Biomarkers in Human Plasma. J Biomol Tech 15, 167-75. PMID: 15331582 (free access)



King, JC. Contributions of Women to Human Nutrition. 2003. J Nutr. 133, 3693-7 (free access)

King, JC. The risk of maternal nutritional depletion and poor outcomes increases in early or closely spaced pregnancies. 2003.  J Nutr. 133 (5 Suppl 2), 1732S-1736S (free access)

Ames, BN. An enthusiasm for metabolism. 2003. J Biol Chem. 278, 4369-80. (free access)