Dr. Rodriguez is a Professor in the Department of Molecular & Cellular Biology and is currently Director of the NIH-sponsored Center of Excellence for Nutritional Genomics at the University of California, Davis. After receiving his Ph.D. at the University of California, Santa Cruz in 1974, he was an A.P. Giannini Foundation Postdoctoral Fellow in the laboratory of Herbert W. Boyer at UC San Francisco Medical Center. While at UCSF, Dr. Rodriguez developed molecular cloning technologies that now serve as the foundation for the biotechnology industry. His 1977 paper on the construction of the cloning vector, pBR322, has been cited more than 5000 times. Dr. Rodriguez joined the faculty at the UC Davis in 1977 and is actively involved in research and teaching at the undergraduate and graduate level. In 1988, Dr. Rodriguez was a Distinguished Visiting Professor in the International Center for Biotechnology at Osaka University, Japan, and in 1991, he was a Visiting Scientist with the Human Genome Project at the Lawrence Livermore National Laboratory. From 1989 to 1992, Dr. Rodriguez established the International Rice Genome Organization — a US/Japan bilateral group that helped establish the framework for sequencing the rice genome. In 2003 he became Director of the Center of Excellence for Nutritional Genomics, a multi-investigator, multi-institutional research program to study the impact of diet-genome interactions on human health. For his leadership in the field of nutritional genomics, Dr. Rodriguez was selected as the 2008 distinguished lecturer by the USDA-ARS Beltsville Center and in 2009 he received an Honorary Doctorate of Science from the Nara Institute of Science and Technology, Nara Japan. Dr. Rodriguez is a member of numerous scientific organizations and committees and he has been an adviser to the NIH and NSF since 1988. He has published numerous articles and books on molecular biology and biotechnology. Dr. Rodriguez currently holds 18 U.S. patents and his latest book, Dietary Regulation of Gene Function and Its Impact on Health (W. Bidlack and R.L. Rodriguez, eds. Taylor & Francis CRC) will appear in 2011. His current research focus is nutritional epigenomics, the study of how dietary factors alter human gene activity by chromatin modification. In addition to his academic duties, Dr. Rodriguez is chairman, CEO of Davis Bioscience Group, a life science technical and management consulting company serving the needs of large multinational corporations as well as the individual bioentrepreneur.
J. and Rodriguez, R.L. 2006. Nutrigenomics:
Discovering the Path to Personalized Nutrition, John Wiley & Sons, New
E.C., Rodriguez, R.L., Dawson, K.
Galvez, A. and Evans, C. 2008. The interaction of genetic polymorphisms with
lifestyle factors: implications for Dietary Prevention. Nutrition and Cancer
Y-M, Jun, H-J, Dawson, K., Rodriguez,
R.L., Roh, M-R, Jun, J., Choi, C-H,
Choi, Shim, J-H, Lee, C-H, Lee, S-J, Park, K-H and Lee, S-J. 2010. Effects of the isoflavone puerarin and
its glycosides on melanogenesis in B16 melanocytes. Eur. Food Res. Technol. DOI
H-J, Chung, M-J, Dawson, K. Rodriguez,
R.L., Houng, S-J, Cho, S-Y, Jeun, J., Kim, J-Y, Kim, K-H, Park, K. W., Kim,
C.-T. and Lee, S-J. 2010. Nutrigenomic Analysis of Hypolipidemic Effects of
Agastache rugosa Essential Oils in HepG2 Cells and C57BL/6 Mice. Food Sci.
A.F., Huang, L., Magbanua, M.M.J. Dawson, K. R. L. Rodriguez. 2011. Differential Expression of Thrombospondin (THBS1)
in Turmorigenic and Nontumorigenic Prostate Epithelial Cells in Response to a
Chromatin-Binding Soy Peptide. Nutrition
and Cancer 63(4):623-636.
H-J, Kim, S., Dawson, K., Choi, D-W, Kim, J-S, Rodriguez, R. L. and Lee, S-J. 2011. Effects of Acute Oral Administration
of Vitamin C on the Mouse Liver Transcriptome.
J. Med. Food. 14:1-14.
A.F., Huang, L., Magbanua, M.M.J. Dawson, K., Nandi, S. and R. L. Rodriguez. 2011. Diet-influenced
Chromatin Modification and Expression of Chemopreventive Genes by the Soy
Peptide, Lunasin, in Nutritional Genomics: Dietary Regulation of Gene Function
on Human Disease. Bidlack, W. and R. L.
Rodriguez, eds. Taylor and Francis/CRC Press, in press.
K., Zhao, L., Adkins, Y., Vemuri, M., Rodriguez,
R.L., Gregg, J.P., Kelley, D. S. and Hwang, D.H. 2011. DHA supplementation suppresses LDL
receptor and oxidized LDL receptor gene expression in blood cells from
hypertriglyceridemic men. J. Nutritional
Biochem. In Press.
Genomics: Dietary Regulation of Gene Function and Human Disease. Bidlack, W. and R. L. Rodriguez, Taylor and Francis/CRC Press, in press. 2011.
June 3, 2010.
Diet-Genome Interactions as a Nutridynamical System: Nutrition Science
at the Edge of Chaos. Annual Conference
of the Korea Nutrition Society, Seoul Korea.
July 2, 2010. Diet-Genome Interactions as a Nutridynamical
System: Nutritional Genomics at the Edge
of Chaos. Griffith University, Brisbane Australia.
September 13, 2010, Diet-Genome Interactions as a
Nutridynamical System: Nutritional
Genomics at the Edge of Chaos. Agricultural Biotechnology International
Conference (ABIC) Saskatoon Saskatewan Canada.
September 23, 2010.
Nutritional Epigenomics: What your grandmother didn’t tell you about
nutrition. National WIC Associate Biennial Conference 2010. Town and Country
Hotel, San Diego CA.
September 29, 2010, Diet-Genome Interactions as a
Nutridynamical System: Nutritional
Genomics at the Edge of Chaos. Meeting of the Council for Responsible
Nutrition, Austin Texas.
November 12, 2010.
Food for Health: Connecting Genetic Diversity and Epigenetics to Improve
Nutrition and Cancer Prevention. Annual
Biomedical Research Conference for Minority Students, Charlotte Convention
Center, Charlotte, North Carolina.
16, 2010. Nutritional Genomics as a
Nutridynamical System: Nutrition Science at the Edge of Chaos. Department of Food Science and Biotechnology,
National Chung Hsing University, Taichung Taiwan.
20, 2010. Global HealthShare Initiative:
The Power of Sharing. Nara Institute of Science and Technology, Nara Japan.
23, 2011. Global HealthShare Initiative:
The Power of Sharing. Research Association for Biotechnology, Ministry of
Economy, Trade and Industry (METI), Tokyo Japan.
24, 2011. Nutritional Genomics as a
Nutridynamical System: Nutrition Science at the Edge of Chaos. Gene Research Center, Graduate School of Life
and Environmental Sciences, University of Tsukuba, Tsukuba Japan.
16, 2011. Global Health and the Power of Sharing. ASCON 13, Accelerating
Science for Universal Health Coverage, International Center for Diarrheal
Disease Research, Bangladesh (ICDDR,B), Dhaka Bangladesh.
23, 2011. Global HealthShare Initiative: The Power of Sharing. Department of
Biotechnology, Ministry of Science and Technology, New Delhi, India.
Issued US Patents:
7,829,277 Methods for identifying compounds that suppress
17. 7,304,208 Expression of human serum albumin (HSA) in monocot
16. 7,045,681 DNA sequences capable of expressing foreign proteins and metabolites in dicot plants and cell culture.
6,991,824 Expression of human milk proteins in transgenic plants
14. 6,919,493 Sugar-regulatory sequences in alpha-amylase genes
13. 6,781,044 Plant selectable marker and plant transformation method
12. 6,680,425 Chimeric plant promoter comprising sugar-regulated
11. 6,288,303 Rice beta-glucanase enzymes and genes
10. 6,284,956 Plant selectable marker and plant transformation method
9. 6,127,145 Production of alpha-1-antitrypsin in plants
8. 6,100,447 Method of barley transformation
7. 6,066,781 Production of mature proteins in plants
6. 6,048,973 Sugar-regulatory sequences in alpha-amylase genes
5. 5,994,628 Process for protein production in plants
4. 5,889,189 Process for protein production in plants
3. 5,888,789 Process for protein production in plants
2. 5,693,506 Process for protein production in plants
1. 4,588,689 Restriction endonuclease XcyI