About Us - About Center Director

RayPhotoSept2011Lrg Raymond Rodriguez
Director and Professor
Center of Excellence for Nutritional Genomics Department of Molecular & Cellular Biology
University of California, Davis

Davis, CA 95616

(530) 752-3263

rlrodriguez@ucdavis.edu
Faculty Profile
   
Dr. Rodriguez is a Professor in the Department of Molecular & Cellular Biology and is currently Director of the NIH-sponsored Center of Excellence for Nutritional Genomics at the University of California, Davis. After receiving his Ph.D. at the University of California, Santa Cruz in 1974, he was an A.P. Giannini Foundation Postdoctoral Fellow in the laboratory of Herbert W. Boyer at UC San Francisco Medical Center. While at UCSF, Dr. Rodriguez developed molecular cloning technologies that now serve as the foundation for the biotechnology industry. His 1977 paper on the construction of the cloning vector, pBR322, has been cited more than 5000 times. Dr. Rodriguez joined the faculty at the UC Davis in 1977 and is actively involved in research and teaching at the undergraduate and graduate level. In 1988, Dr. Rodriguez was a Distinguished Visiting Professor in the International Center for Biotechnology at Osaka University, Japan, and in 1991, he was a Visiting Scientist with the Human Genome Project at the Lawrence Livermore National Laboratory. From 1989 to 1992, Dr. Rodriguez established the International Rice Genome Organization — a US/Japan bilateral group that helped establish the framework for sequencing the rice genome. In 2003 he became Director of the Center of Excellence for Nutritional Genomics, a multi-investigator, multi-institutional research program to study the impact of diet-genome interactions on human health. For his leadership in the field of nutritional genomics, Dr. Rodriguez was selected as the 2008 distinguished lecturer by the USDA-ARS Beltsville Center and in 2009 he received an Honorary Doctorate of Science from the Nara Institute of Science and Technology, Nara Japan. Dr. Rodriguez is a member of numerous scientific organizations and committees and he has been an adviser to the NIH and NSF since 1988. He has published numerous articles and books on molecular biology and biotechnology. Dr. Rodriguez currently holds 18 U.S. patents and his latest book, Dietary Regulation of Gene Function and Its Impact on Health (W. Bidlack and R.L. Rodriguez, eds. Taylor & Francis CRC) will appear in 2011. His current research focus is nutritional epigenomics, the study of how dietary factors alter human gene activity by chromatin modification. In addition to his academic duties, Dr. Rodriguez is chairman, CEO of Davis Bioscience Group, a life science technical and management consulting company serving the needs of large multinational corporations as well as the individual bioentrepreneur.

Recent Publications:

 Kaput, J. and Rodriguez, R.L. 2006. Nutrigenomics: Discovering the Path to Personalized Nutrition, John Wiley & Sons, New Jersey.

 

Nelson, E.C., Rodriguez, R.L., Dawson, K. Galvez, A. and Evans, C. 2008. The interaction of genetic polymorphisms with lifestyle factors: implications for Dietary Prevention. Nutrition and Cancer 60:301-312.

 

Choi, Y-M, Jun, H-J, Dawson, K., Rodriguez, R.L., Roh, M-R, Jun, J., Choi, C-H,  Choi, Shim, J-H, Lee, C-H, Lee, S-J, Park, K-H and Lee, S-J.  2010. Effects of the isoflavone puerarin and its glycosides on melanogenesis in B16 melanocytes. Eur. Food Res. Technol. DOI 10.1007/s00217-010-1251-5.

 

Jun, H-J, Chung, M-J, Dawson, K. Rodriguez, R.L., Houng, S-J, Cho, S-Y, Jeun, J., Kim, J-Y, Kim, K-H, Park, K. W., Kim, C.-T. and Lee, S-J. 2010. Nutrigenomic Analysis of Hypolipidemic Effects of Agastache rugosa Essential Oils in HepG2 Cells and C57BL/6 Mice. Food Sci. Biotechnol. 19(1):219-227.

 

Galvez, A.F., Huang, L., Magbanua, M.M.J. Dawson, K. R. L. Rodriguez. 2011. Differential Expression of Thrombospondin (THBS1) in Turmorigenic and Nontumorigenic Prostate Epithelial Cells in Response to a Chromatin-Binding Soy Peptide.  Nutrition and Cancer 63(4):623-636.

 

Jun, H-J, Kim, S., Dawson, K., Choi, D-W, Kim, J-S, Rodriguez, R. L. and Lee, S-J. 2011. Effects of Acute Oral Administration of Vitamin C on the Mouse Liver Transcriptome.  J. Med. Food. 14:1-14.

 

Galvez, A.F., Huang, L., Magbanua, M.M.J. Dawson, K., Nandi, S. and R. L. Rodriguez. 2011. Diet-influenced Chromatin Modification and Expression of Chemopreventive Genes by the Soy Peptide, Lunasin, in Nutritional Genomics: Dietary Regulation of Gene Function on Human Disease.  Bidlack, W. and R. L. Rodriguez, eds. Taylor and Francis/CRC Press, in press.

 

Dawson, K., Zhao, L., Adkins, Y., Vemuri, M., Rodriguez, R.L., Gregg, J.P., Kelley, D. S. and Hwang, D.H.  2011. DHA supplementation suppresses LDL receptor and oxidized LDL receptor gene expression in blood cells from hypertriglyceridemic men.  J. Nutritional Biochem. In Press.

 

Nutritional Genomics: Dietary Regulation of Gene Function and Human Disease.  Bidlack, W. and R. L. Rodriguez, Taylor and Francis/CRC Press, in press. 2011. 

 

Recent Presentations:

 June 3, 2010.  Diet-Genome Interactions as a Nutridynamical System: Nutrition Science at the Edge of Chaos.  Annual Conference of the Korea Nutrition Society, Seoul Korea.

 July 2, 2010. Diet-Genome Interactions as a Nutridynamical System:  Nutritional Genomics at the Edge of Chaos. Griffith University, Brisbane Australia.

 September 13, 2010, Diet-Genome Interactions as a Nutridynamical System:  Nutritional Genomics at the Edge of Chaos. Agricultural Biotechnology International Conference (ABIC) Saskatoon Saskatewan Canada.

 September 23, 2010.  Nutritional Epigenomics: What your grandmother didn’t tell you about nutrition. National WIC Associate Biennial Conference 2010. Town and Country Hotel, San Diego CA.

 September 29, 2010, Diet-Genome Interactions as a Nutridynamical System:  Nutritional Genomics at the Edge of Chaos. Meeting of the Council for Responsible Nutrition, Austin Texas.

 November 12, 2010.  Food for Health: Connecting Genetic Diversity and Epigenetics to Improve Nutrition and Cancer Prevention.  Annual Biomedical Research Conference for Minority Students, Charlotte Convention Center, Charlotte, North Carolina.

 December 16, 2010.  Nutritional Genomics as a Nutridynamical System: Nutrition Science at the Edge of Chaos.  Department of Food Science and Biotechnology, National Chung Hsing University, Taichung Taiwan.

 December 20, 2010.  Global HealthShare Initiative: The Power of Sharing. Nara Institute of Science and Technology, Nara Japan.

 February 23, 2011.  Global HealthShare Initiative: The Power of Sharing. Research Association for Biotechnology, Ministry of Economy, Trade and Industry (METI), Tokyo Japan.

 February 24, 2011.  Nutritional Genomics as a Nutridynamical System: Nutrition Science at the Edge of Chaos.  Gene Research Center, Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba Japan.

 March 16, 2011. Global Health and the Power of Sharing. ASCON 13, Accelerating Science for Universal Health Coverage, International Center for Diarrheal Disease Research, Bangladesh (ICDDR,B), Dhaka Bangladesh.

 March 23, 2011. Global HealthShare Initiative: The Power of Sharing. Department of Biotechnology, Ministry of Science and Technology, New Delhi, India.


 Issued US Patents:

18.          7,829,277             Methods for identifying compounds that suppress chemically-induced carcinogenesis 

17.          7,304,208             Expression of human serum albumin (HSA) in monocot seeds.

16.          7,045,681             DNA sequences capable of expressing foreign proteins and metabolites in dicot plants and cell culture.

15.          6,991,824             Expression of human milk proteins in transgenic plants

14.          6,919,493             Sugar-regulatory sequences in alpha-amylase genes

13.          6,781,044             Plant selectable marker and plant transformation method

12.          6,680,425             Chimeric plant promoter comprising sugar-regulated sequences

11.          6,288,303             Rice beta-glucanase enzymes and genes

10.          6,284,956             Plant selectable marker and plant transformation method

9.            6,127,145             Production of alpha-1-antitrypsin in plants

8.            6,100,447             Method of barley transformation

7.            6,066,781             Production of mature proteins in plants

6.            6,048,973             Sugar-regulatory sequences in alpha-amylase genes

5.            5,994,628             Process for protein production in plants

4.            5,889,189             Process for protein production in plants

3.            5,888,789             Process for protein production in plants

2.            5,693,506             Process for protein production in plants

1.            4,588,689             Restriction endonuclease XcyI